Alberto A Chiappori Selected Research

S 3304

4/2007

A phase I pharmacokinetic and pharmacodynamic study of s-3304, a novel matrix metalloproteinase inhibitor, in patients with advanced and refractory solid tumors.

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Alberto A Chiappori Research Topics

Disease

19	Neoplasms (Cancer) 10/2021 - 01/2003
10	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2022 - 11/2006
9	Lung Neoplasms (Lung Cancer) 01/2021 - 01/2013
6	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 03/2019 - 01/2003
4	Fatigue 01/2022 - 09/2014
3	Brain Neoplasms (Brain Tumor) 11/2021 - 09/2014
3	Melanoma (Melanoma, Malignant) 01/2021 - 01/2013
3	Diarrhea 10/2016 - 11/2006
2	Neutropenia 10/2016 - 09/2014
2	Pleural Effusion (Pleural Effusions) 09/2014 - 03/2010
2	Exanthema (Rash) 09/2007 - 11/2006
1	Nausea 01/2022
1	Pneumonia (Pneumonitis) 01/2022
1	Neuroendocrine Tumors (Neuroendocrine Tumor) 10/2021
1	Fibrosarcoma 01/2020
1	Adenocarcinoma of Lung 12/2016
1	Anemia 10/2016
1	Dehydration (Water Stress) 10/2016
1	Hypokalemia 10/2016
1	Leukopenia 10/2016
1	Thrombocytopenia (Thrombopenia) 10/2016
1	Autoimmune Diseases (Autoimmune Disease) 04/2016
1	Hypophysitis 04/2016
1	Carcinosarcoma 01/2016
1	Sarcoma (Soft Tissue Sarcoma) 01/2015
1	Acute Kidney Injury (Acute Renal Failure) 09/2014
1	Neoplasm Metastasis (Metastasis) 09/2014
1	Pericardial Effusion 09/2014
1	Myalgia 09/2014
1	Headache (Headaches) 09/2014
1	Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor) 12/2008

Drug/Important Bio-Agent (IBA)

5	Tyrosine Kinase InhibitorsIBA 11/2021 - 01/2014
4	Pharmaceutical PreparationsIBA 01/2020 - 11/2006
4	Biomarkers (Surrogate Marker)IBA 01/2017 - 04/2010
3	ErbB Receptors (EGF Receptor)IBA 10/2019 - 01/2017
3	VaccinesIBA 03/2019 - 06/2010
3	Proteins (Proteins, Gene)FDA Link 12/2017 - 12/2008
3	Paclitaxel (Taxol)FDA LinkGeneric 03/2008 - 01/2006
3	Carboplatin (JM8)FDA LinkGeneric 03/2008 - 01/2006
2	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2022 - 10/2016
2	CrizotinibIBA 11/2021 - 09/2014
2	Anaplastic Lymphoma KinaseIBA 11/2021 - 01/2020
2	Erlotinib Hydrochloride (CP 358,774)FDA Link 10/2019 - 01/2017
2	Neoplasm Antigens (Tumor Antigens)IBA 03/2019 - 04/2016
2	Dasatinib (BMS 354825)FDA Link 01/2019 - 03/2010
2	3- (8- amino- 1- (2- phenylquinolin- 7- yl)imidazo(1,5- a)pyrazin- 3- yl)- 1- methylcyclobutanolIBA 01/2017 - 10/2016
2	Epidermal Growth Factor (EGF)IBA 01/2014 - 01/2013
2	Canertinib (CI 1033)IBA 09/2007 - 11/2006
1	SteroidsIBA 01/2022
1	Alanine (L-Alanine)FDA Link 01/2022
1	Adenosine (Adenocard)FDA LinkGeneric 01/2022
1	spartalizumabIBA 01/2022
1	ensartinibIBA 11/2021
1	Radioisotopes (Radionuclides)IBA 10/2021
1	Peptides (Polypeptides)IBA 10/2021
1	Chelating AgentsIBA 10/2021
1	1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acidIBA 10/2021
1	MetalsIBA 10/2021
1	somatostatin receptor 2IBA 10/2021
1	NivolumabIBA 01/2021
1	Interleukin-2 (IL2)IBA 01/2021
1	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 01/2020
1	Formaldehyde (Formol)FDA Link 01/2020
1	Glycerol KinaseIBA 01/2020
1	RNA (Ribonucleic Acid)IBA 01/2020
1	AfatinibIBA 01/2019
1	DNA (Deoxyribonucleic Acid)IBA 12/2017
1	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 12/2017
1	insulin receptor tyrosine kinaseIBA 01/2017
1	Topotecan (Hycamtin)FDA LinkGeneric 10/2016
1	Alanine Transaminase (SGPT)IBA 10/2016
1	AutoantibodiesIBA 04/2016
1	1-methyltryptophanIBA 04/2016
1	Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA 04/2016
1	Immune Checkpoint InhibitorsIBA 12/2015
1	alectinibIBA 09/2014
1	AntigensIBA 01/2013
1	Mucin-1 (CA 15-3 Antigen)IBA 01/2013
1	INGN 225IBA 06/2010
1	Hydroxymethyl and Formyl TransferasesIBA 04/2010
1	Ribonucleotide Reductases (Ribonucleotide Reductase)IBA 04/2010
1	Thymidylate SynthaseIBA 04/2010
1	Polyglutamic Acid (Polyglutamate)IBA 04/2010
1	Phosphotransferases (Kinase)IBA 03/2010
1	Cyclin D3IBA 12/2008
1	Retinoblastoma ProteinIBA 12/2008
1	Proto-Oncogene Proteins c-kit (Proto-Oncogene Protein c-kit)IBA 12/2008
1	Cyclin D1IBA 12/2008
1	Endothelin A ReceptorIBA 03/2008
1	AtrasentanIBA 03/2008
1	polyglutamate camptothecinIBA 10/2007
1	Glutamic Acid (Glutamate)FDA Link 10/2007
1	PlatinumIBA 09/2007

Therapy/Procedure

9	Drug Therapy (Chemotherapy) 03/2019 - 01/2003
5	Therapeutics 10/2021 - 03/2008
1	Cell- and Tissue-Based Therapy (Cell Therapy) 01/2021
1	Adjuvant Chemotherapy 12/2016
1	Injections 01/2015
1	Aftercare (After-Treatment) 01/2014
1	Immunotherapy 01/2013